As we age, our skin naturally loses collagen and elastin, leading to thinning, sagging, and wrinkling. While there are many treatments available, two stand out for their regenerative, long-lasting results: PDGF-BB (Platelet-Derived Growth Factor-BB) and Hyperdilute Radiesse. These advanced therapies stimulate your body’s own healing response to improve skin texture, tone, and firmness, with minimal downtime.
What Is PDGF-BB?
PDGF-BB is a potent growth factor known for stimulating the production of fibroblasts and collagen. It plays a key role in:
- Tissue repair and regeneration
- Angiogenesis (formation of new blood vessels)
- Collagen synthesis
- Wound healing
PDGF-BB can be derived from platelets (as part of PRP or PRF) or from lab-engineered growth factor serums. When injected or microneedled into the skin, it acts as a signaling molecule to turn on your body’s repair and renewal mechanisms, effectively rejuvenating skin at a cellular level.
What Is Hyperdilute Radiesse?
Radiesse® is a dermal filler made of calcium hydroxylapatite (CaHA) microspheres suspended in a gel. When hyperdiluted, it’s mixed with saline and/or lidocaine to create a smooth, injectable biostimulatory treatment rather than a traditional filler.
Hyperdilute Radiesse:
- Acts as a collagen stimulator, not a volumizer
- Improves skin texture, elasticity, and thickness
- Works well in thin, crepey, or lax skin areas
- It is ideal for face, neck, décolletage, arms, abdomen, knees, and more
Why Combine PDGF-BB with Hyperdilute Radiesse?
This combination therapy harnesses both biostimulation and cellul
- Radiesse activates fibroblasts to rebuild structural support and collagen
- PDGF-BB enhances cellular communication, accelerating tissue repair and remodeling
- Together, they reduce fine lines, improve elasticity, and restore youthful skin tone from the inside out
Many clinics find that combining these two results in more rapid and pronounced results than either one alone.
Who Is a Good Candidate?
This treatment is excellent for those noticing:
- Skin laxity or crepey skin
- Loss of firmness in the neck, face, or body
- Sun damage or uneven skin tone
- Mild-to-moderate volume loss without needing full fillers
It’s also a great option for patients seeking non-surgical rejuvenation with natural-looking results.
What to Expect During Treatment
At Snider Wellness and Aesthetics, your treatment typically involves:
- Consultation and skin evaluation
- Application of topical numbing if needed
- Injection of hyperdilute Radiesse, followed by or combined with PDGF-BB, using a cannula or microneedling technique
- Light massage to evenly distribute the product
Most patients experience only mild swelling or redness, and return to normal activities the same day or the following day.
Results and Frequency
- Results begin within 2-4 weeks, with continued improvement over 3-6 months
- Most patients need 1-2 treatments, spaced 4-6 weeks apart, with maintenance annually
- Improvements are long-lasting, as new collagen and elastin form
Why Choose Snider Wellness and Aesthetics?
At Snider Wellness and Aesthetics, we specialize in regenerative skin therapies that go beyond surface-level beauty. Our advanced combination protocols using PDGF-BB and hyperdilute Radiesse deliver real, biologically driven results. We believe in addressing the root causes of skin aging for naturally radiant, healthy skin.
Book your consultation today to see if this collagen-stimulating duo is right for you.
